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KATNAL2
Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.6.4.3; Hydrolase |
| Chromosomal Location of human Ortholog: 18q21.1 |
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Cellular Component:
cytoplasm; katanin complex; microtubule; microtubule cytoskeleton; spindle; spindle pole
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Molecular Function:
ATP binding; ATP hydrolysis activity; isomerase activity; microtubule binding; microtubule severing ATPase activity; protein binding
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Biological Process:
cytoplasmic microtubule organization; microtubule severing
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Reference #:
Q8IYT4
(UniProtKB)
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Alt. Names/Synonyms: DKFZp667C165; katanin catalytic subunit A like 2; katanin catalytic subunit A1 like 2; Katanin p60 ATPase-containing subunit A-like 2; katanin p60 subunit A like 2; Katanin p60 subunit A-like 2; KATL2; KATNAL2; MGC33211; p60 katanin-like 2
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Gene Symbols: KATNAL2
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Molecular weight:
61,253 Da
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Basal Isoelectric point:
7.22
Predict pI for various phosphorylation states
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