PPP1R3A Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase. Interacts with PPP1CC catalytic subunit of PP1, and associates with glycogen. Skeletal muscle and heart. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Protein phosphatase, regulatory subunit
Chromosomal Location of Human Ortholog: 6|6 A1
Cellular Component:  integral component of membrane; membrane
Molecular Function:  protein serine/threonine phosphatase activity
Biological Process:  carbohydrate metabolic process; glycogen metabolic process
Reference #:  Q99MR9 (UniProtKB)
Alt. Names/Synonyms: GM; MGC124391; MGC124392; Pp1g; Ppp1r3a; PPR3A; Protein phosphatase 1 glycogen-associated regulatory subunit; Protein phosphatase 1 regulatory subunit 3A; protein phosphatase 1, regulatory (inhibitor) subunit 3A; Protein phosphatase type-1 glycogen targeting subunit; RG1; RGL
Gene Symbols: Ppp1r3a
Molecular weight: 121,435 Da
Basal Isoelectric point: 4.99  Predict pI for various phosphorylation states
Select Structure to View Below

PPP1R3A

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene