GATAD2B Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development. Widely expressed. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 3|3 F1
Cellular Component:  nucleoplasm; nucleus; NuRD complex
Molecular Function:  metal ion binding; protein binding; sequence-specific DNA binding; zinc ion binding
Biological Process:  negative regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated
Reference #:  Q8VHR5 (UniProtKB)
Alt. Names/Synonyms: AL118180; C430014D17Rik; GATA zinc finger domain containing 2B; GATA zinc finger domain-containing protein 2B; Gatad2b; KIAA1150; mKIAA1150; p66/p68; P66B; p66be; P66beta; transcription repressor p66 beta component of the MeCP1 complex; transcription repressor p66 component of the MeCP1 complex; Transcriptional repressor p66-beta
Gene Symbols: Gatad2b
Molecular weight: 65,411 Da
Basal Isoelectric point: 9.73  Predict pI for various phosphorylation states
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GATAD2B

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene