Exportin-6 a protein of the exportin family. Exportins recruit cargo from the nucleoplasm in the presence of RAN-GTP and form ternary export complexes. These complexes are transported through nuclear pore complexes to the cytoplasm, where GTP is hydrolyzed and the export complex is disassembled. Exportin 6 mediates nuclear export of profilin-actin complexes. Note: This description may include information from UniProtKB.
Protein type: Karyopherin; Nuclear export; Nuclear import
Chromosomal Location of Human Ortholog: 7|7 F3
Cellular Component:  cytoplasm; cytosol; nucleolus; nucleus; plasma membrane; protein-containing complex
Molecular Function:  nuclear export signal receptor activity; Ran GTPase binding
Biological Process:  intracellular protein transport; protein export from nucleus; protein transport
Reference #:  Q924Z6 (UniProtKB)
Alt. Names/Synonyms: 2610005L19Rik; AI854665; AL022631; C230091E20Rik; Exp6; exportin 6; Exportin-6; mKIAA0370; R75304; RAN binding protein 20; Ran-binding protein 20; Ranbp20; Xpo6
Gene Symbols: Xpo6
Molecular weight: 128,664 Da
Basal Isoelectric point: 5.94  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene