SG2NA a protein of the WD-repeat striatin family. Mainly expressed within neurons and thought to act both as scaffolds and as Ca(2+)-dependent signalling proteins. May interact with protein phosphatase 2A. Two alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit; Transcription factor
Chromosomal Location of Human Ortholog: 14q12
Cellular Component:  dendrite; FAR/SIN/STRIPAK complex; Golgi apparatus; neuronal cell body; nucleoplasm; plasma membrane; protein-containing complex
Molecular Function:  armadillo repeat domain binding; calmodulin binding; protein binding; protein phosphatase 2A binding; protein-containing complex binding; Rho GTPase binding
Biological Process:  negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of transcription, DNA-templated; response to estradiol
Reference #:  Q13033 (UniProtKB)
Alt. Names/Synonyms: Cell cycle autoantigen SG2NA; cell cycle S/G2 nuclear autoantigen; GS2NA; nuclear autoantigen; S/G2 antigen; SG2NA; striatin, calmodulin binding protein 3; Striatin-3; STRN3
Gene Symbols: STRN3
Molecular weight: 87,209 Da
Basal Isoelectric point: 5.17  Predict pI for various phosphorylation states
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SG2NA

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein