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GTSE1
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression. Note: This description may include information from UniProtKB.
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| Protein type: Apoptosis; Cell cycle regulation |
| Chromosomal Location of Human Ortholog: 22q13.31 |
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Cellular Component:
cytoplasmic microtubule; cytosol; nucleoplasm
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Molecular Function:
protein binding
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Biological Process:
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; microtubule-based process; positive regulation of cell migration; positive regulation of protein export from nucleus; positive regulation of protein localization to nucleus; protein stabilization; regulation of cell cycle G2/M phase transition
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Reference #:
Q9NYZ3
(UniProtKB)
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Alt. Names/Synonyms: B99; G-2 and S-phase expressed 1; G2 and S phase-expressed protein 1; G2 and S-phase expressed 1; GTSE-1; GTSE1; Protein B99 homolog
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Gene Symbols: GTSE1
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Molecular weight:
76,645 Da
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Basal Isoelectric point:
9.45
Predict pI for various phosphorylation states
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