GTSE1 May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Cell cycle regulation
Chromosomal Location of Human Ortholog: 22q13.31
Cellular Component:  cytoplasmic microtubule; cytosol; nucleoplasm
Molecular Function:  protein binding
Biological Process:  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; microtubule-based process; positive regulation of cell migration; positive regulation of protein export from nucleus; positive regulation of protein localization to nucleus; protein stabilization; regulation of cell cycle G2/M phase transition
Reference #:  Q9NYZ3 (UniProtKB)
Alt. Names/Synonyms: B99; G-2 and S-phase expressed 1; G2 and S phase-expressed protein 1; G2 and S-phase expressed 1; GTSE-1; GTSE1; Protein B99 homolog
Gene Symbols: GTSE1
Molecular weight: 76,645 Da
Basal Isoelectric point: 9.45  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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