GATAD2B Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development. Widely expressed. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component:  nuclear speck; nucleoplasm
Molecular Function:  DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding; zinc ion binding
Disease: Mental Retardation, Autosomal Dominant 18
Reference #:  Q8WXI9 (UniProtKB)
Alt. Names/Synonyms: FLJ37346; GATA zinc finger domain containing 2B; GATA zinc finger domain-containing protein 2B; GATAD2B; KIAA1150; MGC138257; MGC138285; MRD18; p66/p68; P66B; P66beta; p68; RP11-216N14.6; transcription repressor p66 beta component of the MeCP1 complex; Transcriptional repressor p66-beta
Gene Symbols: GATAD2B
Molecular weight: 65,261 Da
Basal Isoelectric point: 9.73  Predict pI for various phosphorylation states
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GATAD2B

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene