EPB41L1 iso2 May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 3q42
Cellular Component:  cytoplasm; cytoskeleton; plasma membrane; postsynaptic density; protein-containing complex; synaptic membrane
Molecular Function:  actin binding; cytoskeletal protein binding; signaling receptor binding; structural molecule activity
Biological Process:  actomyosin structure organization; cortical actin cytoskeleton organization
Reference #:  Q9WTP0-2 (UniProtKB)
Alt. Names/Synonyms: Band 4.1-like protein 1; Epb41l1; EPB41L1 iso2; erythrocyte protein band 4.1-like 1
Gene Symbols: Epb41l1
Molecular weight: 171,011 Da
Basal Isoelectric point: 5.23  Predict pI for various phosphorylation states
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EPB41L1 iso2

Protein Structure Not Found.

Cross-references to other databases:  Pfam  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene