TNNI2
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Belongs to the troponin I family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
Protein type: Motility/polarity/chemotaxis |
Chromosomal Location of Human Ortholog: 1q41 |
Cellular Component:
nucleus; troponin complex
|
Molecular Function:
actin binding; troponin T binding
|
Biological Process:
cardiac muscle contraction; muscle contraction; positive regulation of transcription, DNA-templated; regulation of muscle contraction; skeletal muscle contraction
|
Reference #:
P27768
(UniProtKB)
|
Alt. Names/Synonyms: TNNI2; Troponin I, fast skeletal muscle
|
Gene Symbols: Tnni2
|
Molecular weight:
21,328 Da
|
Basal Isoelectric point:
8.86
Predict pI for various phosphorylation states
|