TNNI2 Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Belongs to the troponin I family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1q41
Cellular Component:  nucleus; troponin complex
Molecular Function:  actin binding; troponin T binding
Biological Process:  cardiac muscle contraction; muscle contraction; positive regulation of transcription, DNA-templated; regulation of muscle contraction; skeletal muscle contraction
Reference #:  P27768 (UniProtKB)
Alt. Names/Synonyms: TNNI2; Troponin I, fast skeletal muscle
Gene Symbols: Tnni2
Molecular weight: 21,328 Da
Basal Isoelectric point: 8.86  Predict pI for various phosphorylation states
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TNNI2

Protein Structure Not Found.


Cross-references to other databases:  Reactome  |  BioGPS  |  Pfam  |  UniProtKB  |  Entrez-Gene