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TPH2
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. Brain specific. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Amino Acid Metabolism - tryptophan; EC 1.14.16.4; Oxidoreductase |
| Chromosomal Location of rat Ortholog: 7q22 |
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Cellular Component:
neuron projection
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Molecular Function:
iron ion binding; tryptophan 5-monooxygenase activity
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Biological Process:
aromatic amino acid metabolic process; cellular response to lithium ion; circadian rhythm; response to activity; response to calcium ion; response to estrogen; response to glucocorticoid; response to nutrient levels; serotonin biosynthetic process
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Reference #:
Q8CGU9
(UniProtKB)
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Alt. Names/Synonyms: TPH2; Tryptophan 5-hydroxylase 2
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Gene Symbols: Tph2
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Molecular weight:
55,621 Da
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Basal Isoelectric point:
5.88
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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