PTDSS2
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine. Belongs to the phosphatidyl serine synthase family. Note: This description may include information from UniProtKB.
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Protein type: EC 2.7.8.29; Lipid Metabolism - glycerophospholipid; Membrane protein, integral; Membrane protein, multi-pass; Transferase |
Chromosomal Location of rat Ortholog: 1q41 |
Cellular Component:
endoplasmic reticulum membrane; membrane
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Molecular Function:
CDP-diacylglycerol-serine O-phosphatidyltransferase activity; L-serine-phosphatidylethanolamine phosphatidyltransferase activity
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Biological Process:
phosphatidylserine biosynthetic process
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Reference #:
B2GV22
(UniProtKB)
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Alt. Names/Synonyms: Phosphatidylserine synthase 2; PTDSS2
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Gene Symbols: Ptdss2
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Molecular weight:
54,722 Da
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Basal Isoelectric point:
6.13
Predict pI for various phosphorylation states
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