PTDSS2 Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine. Belongs to the phosphatidyl serine synthase family. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.8.29; Lipid Metabolism - glycerophospholipid; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of rat Ortholog: 1q41
Cellular Component:  endoplasmic reticulum membrane; membrane
Molecular Function:  CDP-diacylglycerol-serine O-phosphatidyltransferase activity; L-serine-phosphatidylethanolamine phosphatidyltransferase activity
Biological Process:  phosphatidylserine biosynthetic process
Reference #:  B2GV22 (UniProtKB)
Alt. Names/Synonyms: Phosphatidylserine synthase 2; PTDSS2
Gene Symbols: Ptdss2
Molecular weight: 54,722 Da
Basal Isoelectric point: 6.13  Predict pI for various phosphorylation states
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PTDSS2

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  Reactome  |  BioGPS  |  Pfam  |  UniProtKB  |  Entrez-Gene