XAB2 Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing. Belongs to the crooked-neck family. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; Spliceosome
Chromosomal Location of rat Ortholog: 12p12
Cellular Component:  catalytic step 2 spliceosome; intracellular membrane-bounded organelle; nucleoplasm; nucleus; post-mRNA release spliceosomal complex; Prp19 complex; U2-type catalytic step 2 spliceosome
Biological Process:  blastocyst development; cerebral cortex development; DNA-templated transcription; generation of catalytic spliceosome for first transesterification step; mRNA splicing, via spliceosome; transcription-coupled nucleotide-excision repair
Reference #:  Q99PK0 (UniProtKB)
Alt. Names/Synonyms: Pre-mRNA-splicing factor SYF1; XAB2
Gene Symbols: Xab2
Molecular weight: 99,998 Da
Basal Isoelectric point: 5.87  Predict pI for various phosphorylation states
Select Structure to View Below

XAB2

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  Reactome  |  BioGPS  |  Pfam  |  UniProtKB  |  Entrez-Gene