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DZIP1L
Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane. Belongs to the DZIP C2H2-type zinc-finger protein family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: C2H2-type zinc finger protein |
| Chromosomal Location of rat Ortholog: 8q31 |
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Cellular Component:
axoneme; centriole; ciliary basal body; cilium; cytoplasm; cytoskeleton
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Molecular Function:
metal ion binding
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Biological Process:
ciliary transition zone assembly; cilium assembly; floor plate development; neural tube patterning; protein localization to cilium; protein localization to organelle; regulation of protein localization; smoothened signaling pathway
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Reference #:
Q5XIA0
(UniProtKB)
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Alt. Names/Synonyms: Cilium assembly protein DZIP1L; DZIP1L; Zinc finger protein DZIP1L
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Gene Symbols: Dzip1l
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Molecular weight:
88,025 Da
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Basal Isoelectric point:
8.27
Predict pI for various phosphorylation states
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