KIF23 iso2 a member of kinesin-like protein family. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. Localizes to the interzone of mitotic spindles. The kinesin family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. Alternate splicing results in two different human isoforms. Note: This description may include information from UniProtKB.
Protein type: Microtubule-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 15q23
Cellular Component:  centrosome; cytosol; Flemming body; intercellular bridge; kinesin complex; microtubule; midbody; nucleoplasm; nucleus; spindle
Molecular Function:  ATP binding; ATPase activity; microtubule binding; microtubule motor activity; protein binding
Biological Process:  actomyosin contractile ring assembly; antigen processing and presentation of exogenous peptide antigen via MHC class II; microtubule-based movement; mitotic cytokinesis; mitotic spindle elongation; mitotic spindle midzone assembly; plus-end-directed vesicle transport along microtubule; positive regulation of cytokinesis; retrograde vesicle-mediated transport, Golgi to ER
Reference #:  Q02241-2 (UniProtKB)
Alt. Names/Synonyms: CHO1; KIF23; kinesin family member 23; kinesin-like 5 (mitotic kinesin-like protein 1); Kinesin-like protein 5; Kinesin-like protein KIF23; KNSL5; mitotic kinesin-like 1; Mitotic kinesin-like protein 1; MKLP-1; MKLP1
Gene Symbols: KIF23
Molecular weight: 98,105 Da
Basal Isoelectric point: 8.69  Predict pI for various phosphorylation states
Select Structure to View Below

KIF23 iso2

Protein Structure Not Found.


Cross-references to other databases:  cBioPortal  |  Wikipedia  |  Pfam  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein