ABCC9 Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family
Chromosomal Location of Human Ortholog: 4q44
Cellular Component:  acrosomal vesicle; integral component of membrane; inward rectifying potassium channel; membrane; mitochondrion; plasma membrane; sarcolemma; sarcomere; T-tubule
Molecular Function:  ATP binding; ATPase activity, coupled to transmembrane movement of substances; drug binding; identical protein binding; ion channel binding; potassium channel activity; potassium channel regulator activity; protein binding; sulfonylurea receptor activity; syntaxin binding
Biological Process:  defense response to virus; potassium ion import across plasma membrane; potassium ion transmembrane transport; potassium ion transport; response to drug; substrate-dependent cell migration, cell contraction; transmembrane transport
Reference #:  Q9JJ67 (UniProtKB)
Alt. Names/Synonyms: Abcc9; ATP-binding cassette sub-family C member 9; ATP-binding cassette transporter sub-family C member 9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; Sulfonylurea receptor 2; Sulphonylurea receptor 2b; Sur2; SUR2b
Gene Symbols: Abcc9
Molecular weight: 174,365 Da
Basal Isoelectric point: 7.05  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene