IFRD1
Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal. Belongs to the IFRD family. Expressed in a variety of tissues. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
Chromosomal Location of human Ortholog: 7q31.1 |
Cellular Component:
nucleus; sarcoplasm
|
Biological Process:
muscle cell differentiation; myoblast fate determination; negative regulation of axon extension; negative regulation of collateral sprouting; skeletal muscle tissue regeneration; striated muscle tissue development
|
Reference #:
O00458
(UniProtKB)
|
Alt. Names/Synonyms: 12-O-tetradecanoylphorbol-13-acetate-induced sequence 7; IFRD1; interferon related developmental regulator 1; Interferon-related developmental regulator 1; Nerve growth factor-inducible protein PC4; PC4; pheochromocytoma cell-4; TIS7; TPA induced sequence 7
|
Gene Symbols: IFRD1
|
Molecular weight:
50,269 Da
|
Basal Isoelectric point:
6.8
Predict pI for various phosphorylation states
|