IFRD1 Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal. Belongs to the IFRD family. Expressed in a variety of tissues. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of human Ortholog: 7q31.1
Cellular Component:  nucleus; sarcoplasm
Biological Process:  muscle cell differentiation; myoblast fate determination; negative regulation of axon extension; negative regulation of collateral sprouting; skeletal muscle tissue regeneration; striated muscle tissue development
Reference #:  O00458 (UniProtKB)
Alt. Names/Synonyms: 12-O-tetradecanoylphorbol-13-acetate-induced sequence 7; IFRD1; interferon related developmental regulator 1; Interferon-related developmental regulator 1; Nerve growth factor-inducible protein PC4; PC4; pheochromocytoma cell-4; TIS7; TPA induced sequence 7
Gene Symbols: IFRD1
Molecular weight: 50,269 Da
Basal Isoelectric point: 6.8  Predict pI for various phosphorylation states
Select Structure to View Below

IFRD1

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein