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EHOC-1
May play a role in vesicular transport from endoplasmic reticulum to Golgi. Belongs to the TMEM1 family. Expressed in all tissues examined. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Chromosomal Location of human Ortholog: 21q22.3 |
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Cellular Component:
cytoplasm; cytosol; TRAPP complex; TRAPPII protein complex
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Molecular Function:
protein binding
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Biological Process:
early endosome to Golgi transport; endoplasmic reticulum to Golgi vesicle-mediated transport; intra-Golgi vesicle-mediated transport; vesicle coating; vesicle tethering
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Disease: Neurodevelopmental Disorder With Microcephaly, Short Stature, And Speech Delay
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Reference #:
P48553
(UniProtKB)
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Alt. Names/Synonyms: EHOC-1; EHOC1; Epilepsy holoprosencephaly candidate 1 protein; epilepsy holoprosencephaly candidate-1 protein; FLJ54223; FLJ54817; FLJ55683; GT334; MGC126777; Protein GT334; TMEM1; TPC10; trafficking protein particle complex 10; Trafficking protein particle complex subunit 10; trafficking protein particle complex subunit 130; Trafficking protein particle complex subunit TMEM1; transmembrane protein 1; Transport protein particle subunit TMEM1; TRAPP 130 kDa subunit; TRAPP subunit TMEM1; TRAPPC10; TRS130; TRS30
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Gene Symbols: TRAPPC10
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Molecular weight:
142,189 Da
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Basal Isoelectric point:
5.68
Predict pI for various phosphorylation states
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