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Bright
Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. Widely expressed, with highest expression in skeletal muscle, thalamus, and colon. Note: This description may include information from UniProtKB.
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| Protein type: Transcription factor |
| Chromosomal Location of human Ortholog: 19p13.3 |
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Cellular Component:
cytosol; membrane raft; nucleoplasm; nucleus
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Molecular Function:
chromatin binding; DNA binding; identical protein binding; protein binding; transcription coregulator activity
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Biological Process:
DNA-templated transcription; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II
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Reference #:
Q99856
(UniProtKB)
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Alt. Names/Synonyms: ARI3A; ARID domain-containing 3A; ARID domain-containing protein 3A; ARID3A; AT rich interactive domain 3A (BRIGHT- like) protein; AT rich interactive domain 3A (BRIGHT-like); AT-rich interaction domain 3A; AT-rich interactive domain-containing protein 3A; B-cell regulator of IgH transcription; Bright; dead ringer-like 1; Dead ringer-like protein 1; DRIL1; DRIL3; DRX; E2F-binding protein 1; E2FBP1
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Gene Symbols: ARID3A
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Molecular weight:
62,889 Da
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Basal Isoelectric point:
4.84
Predict pI for various phosphorylation states
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