MYO6 a molecular motor involved in intracellular vesicle and organelle transport. It is one of the so-called unconventional myosins. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 9 E1|9 43.98 cM
Cellular Component:  apical part of cell; axon; brush border; cell projection; cell soma; clathrin-coated endocytic vesicle; clathrin-coated pit; cytoplasm; cytoplasmic vesicle; DNA-directed RNA polymerase II, holoenzyme; endocytic vesicle; filamentous actin; Golgi apparatus; intracellular membrane-bound organelle; membrane; microvillus; myosin complex; nuclear membrane; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; ruffle; synapse; vesicle membrane
Molecular Function:  actin binding; actin filament binding; ATP binding; calmodulin binding; identical protein binding; microtubule binding; microtubule motor activity; motor activity; nucleotide binding; protein binding
Biological Process:  auditory receptor cell differentiation; dendrite development; DNA damage response, signal transduction by p53 class mediator; endocytosis; glutamate secretion; inner ear development; inner ear morphogenesis; locomotory behavior; microtubule-based movement; positive regulation of transcription from RNA polymerase II promoter; protein targeting; protein transport; regulation of secretion; regulation of synaptic plasticity; response to drug; sensory perception of sound; synaptic transmission; synaptogenesis
Reference #:  Q64331 (UniProtKB)
Alt. Names/Synonyms: BC029719; Myo6; myosin VI; Myosin-VI; OTTMUSP00000019172; Snell's waltzer; Sv; Unconventional myosin-6; Unconventional myosin-VI
Gene Symbols: Myo6
Molecular weight: 146,409 Da
Basal Isoelectric point: 9.01  Predict pI for various phosphorylation states
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MYO6

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene