OSGIN1 Regulates the differentiation and proliferation through the regulation of cell death. Belongs to the OKL38 family. Ubiquitous. Highest expression in the ovary, testis, kidney, skeletal muscle and liver (PubMed:11459809, PubMed:14570898, PubMed:15569677). Weakly expressed in spleen, heart, kidney, and pancreas (PubMed:15569677). Highly expressed in tumor cells (at protein level) (PubMed:15569677). Note: This description may include information from UniProtKB.
Chromosomal Location of human Ortholog: 16q23.3
Cellular Component: 
Molecular Function:  growth factor activity; protein binding
Biological Process:  cell differentiation; negative regulation of cell growth; positive regulation of apoptotic process; regulation of apoptotic process; regulation of cell migration; regulation of cell population proliferation; signal transduction
Reference #:  Q9UJX0 (UniProtKB)
Alt. Names/Synonyms: BDGI; BMSC-derived growth inhibitor; bone marrow stromal cell-derived growth inhibitor; huOKL38; OKL38; OSGI1; OSGIN1; Ovary, kidney and liver protein 38; oxidative stress induced growth inhibitor 1; Oxidative stress-induced growth inhibitor 1; pregnancy induced growth inhibitor; Pregnancy-induced growth inhibitor OKL38
Gene Symbols: OSGIN1
Molecular weight: 51,992 Da
Basal Isoelectric point: 6.63  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene