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OSGIN1
Regulates the differentiation and proliferation through the regulation of cell death. Belongs to the OKL38 family. Ubiquitous. Highest expression in the ovary, testis, kidney, skeletal muscle and liver (PubMed:11459809, PubMed:14570898, PubMed:15569677). Weakly expressed in spleen, heart, kidney, and pancreas (PubMed:15569677). Highly expressed in tumor cells (at protein level) (PubMed:15569677). Note: This description may include information from UniProtKB.
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| Chromosomal Location of human Ortholog: 16q23.3 |
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Cellular Component:
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Molecular Function:
growth factor activity; protein binding
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Biological Process:
cell differentiation; negative regulation of cell growth; positive regulation of apoptotic process; regulation of apoptotic process; regulation of cell migration; regulation of cell population proliferation; signal transduction
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Reference #:
Q9UJX0
(UniProtKB)
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Alt. Names/Synonyms: BDGI; BMSC-derived growth inhibitor; bone marrow stromal cell-derived growth inhibitor; huOKL38; OKL38; OSGI1; OSGIN1; Ovary, kidney and liver protein 38; oxidative stress induced growth inhibitor 1; Oxidative stress-induced growth inhibitor 1; pregnancy induced growth inhibitor; Pregnancy-induced growth inhibitor OKL38
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Gene Symbols: OSGIN1
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Molecular weight:
51,992 Da
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Basal Isoelectric point:
6.63
Predict pI for various phosphorylation states
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