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OGDHL
Belongs to the alpha-ketoglutarate dehydrogenase family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - citrate (TCA) cycle; EC 1.2.4.-; Mitochondrial; Oxidoreductase |
| Chromosomal Location of human Ortholog: 10q11.23 |
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Cellular Component:
mitochondrial matrix; mitochondrion; oxoglutarate dehydrogenase complex
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Molecular Function:
metal ion binding; oxoglutarate dehydrogenase (succinyl-transferring) activity; protein binding; thiamine pyrophosphate binding
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Biological Process:
2-oxoglutarate metabolic process; glycolytic process; tricarboxylic acid cycle
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Disease: Yoon-bellen Neurodevelopmental Syndrome
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Reference #:
Q9ULD0
(UniProtKB)
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Alt. Names/Synonyms: 2-oxoglutarate dehydrogenase complex component E1-like; 2-oxoglutarate dehydrogenase-like, mitochondrial; Alpha-ketoglutarate dehydrogenase-like; KIAA1290; OGDC-E1-like; OGDHL; oxoglutarate dehydrogenase L; oxoglutarate dehydrogenase like; oxoglutarate dehydrogenase-like
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Gene Symbols: OGDHL
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Molecular weight:
114,481 Da
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Basal Isoelectric point:
6.18
Predict pI for various phosphorylation states
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