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MTFMT
Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism. Belongs to the Fmt family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cofactor and Vitamin Metabolism - one carbon pool by folate; EC 2.1.2.9; Methyltransferase; Mitochondrial |
| Chromosomal Location of human Ortholog: 15q22.31 |
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Cellular Component:
mitochondrion
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Molecular Function:
methionyl-tRNA formyltransferase activity
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Biological Process:
conversion of methionyl-tRNA to N-formyl-methionyl-tRNA; translational initiation
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Disease: Combined Oxidative Phosphorylation Deficiency 15; Mitochondrial Complex I Deficiency, Nuclear Type 27
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Reference #:
Q96DP5
(UniProtKB)
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Alt. Names/Synonyms: COXPD15; FMT; FMT1; MC1DN27; Methionyl-tRNA formyltransferase, mitochondrial; mitochondrial methionyl-tRNA formyltransferase; MTFMT
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Gene Symbols: MTFMT
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Molecular weight:
43,832 Da
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Basal Isoelectric point:
9.7
Predict pI for various phosphorylation states
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