MAZ May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins. Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level). 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; RNA-binding; Transcription factor
Cellular Component: 
Reference #:  O97600 (UniProtKB)
Alt. Names/Synonyms: MAZ; MAZI; Myc-associated zinc finger protein; MYC-associated zinc finger protein (purine-binding transcription factor); SAF-1; Serum amyloid A-activating factor SAF-1
Gene Symbols: MAZ
Molecular weight: 48,999 Da
Basal Isoelectric point: 9.32  Predict pI for various phosphorylation states
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MAZ

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene