MMD2 a member of the PAQR (progestin and adipoQ receptor) family. Members of this family are evolutionarily conserved with significant sequence identity to bacterial hemolysin-like proteins and are defined by a set of seven transmembrane domains. The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 7p22.1
Cellular Component:  Golgi membrane; integral component of membrane; perinuclear region of cytoplasm
Molecular Function:  protein kinase activity
Biological Process:  positive regulation of neuron differentiation; positive regulation of protein kinase activity; positive regulation of Ras protein signal transduction; protein amino acid phosphorylation; regulation of protein localization
Reference #:  Q8IY49 (UniProtKB)
Alt. Names/Synonyms: FLJ37205; MMD2; Monocyte to macrophage differentiation factor 2; monocyte to macrophage differentiation-associated 2; monocyte-to-macrophage differentiation factor 2; PAQR10; PAQRA; Progestin and adipoQ receptor family member 10; Progestin and adipoQ receptor family member X
Gene Symbols: MMD2
Molecular weight: 31,264 Da
Basal Isoelectric point: 8.97  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB