KCNAB3 Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5. Belongs to the shaker potassium channel beta subunit family. Brain specific. Most prominent expression in cerebellum. Weaker signals detected in cortex, occipital lobe, frontal lobe and temporal lobe. Not detected in spinal cord, heart, lung, liver, kidney, pancreas, placenta and skeletal muscle. Note: This description may include information from UniProtKB.
Protein type: Channel, potassium
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component:  cytoplasm; integral component of membrane; plasma membrane
Molecular Function:  potassium channel regulator activity; voltage-gated potassium channel activity
Biological Process:  potassium ion transmembrane transport; potassium ion transport; regulation of ion transmembrane transport
Reference #:  O43448 (UniProtKB)
Alt. Names/Synonyms: AKR6A9; K(+) channel subunit beta-3; K+ channel beta-3 subunit; KCAB3; KCNA3.1B; KCNA3B; KCNAB3; Kv-beta-3; MGC116886; potassium channel, voltage gated subfamily A regulatory beta subunit 3; potassium channel, voltage-dependent, beta-3 subunit; potassium voltage-gated channel subfamily A regulatory beta subunit 3; potassium voltage-gated channel, shaker-related subfamily, beta member 3; Voltage-gated potassium channel subunit beta-3
Gene Symbols: KCNAB3
Molecular weight: 43,670 Da
Basal Isoelectric point: 8.87  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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