LUM Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. Cornea and other tissues. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of mouse Ortholog: 10 C3|10 50.32 cM
Cellular Component:  extracellular matrix; extracellular region; fibrillar collagen trimer
Molecular Function:  collagen binding; extracellular matrix structural constituent conferring compression resistance
Biological Process:  collagen fibril organization; positive regulation of transcription by RNA polymerase II; positive regulation of transforming growth factor beta1 production; visual perception
Reference #:  P51885 (UniProtKB)
Alt. Names/Synonyms: Keratan sulfate proteoglycan lumican; KSPG lumican; Lcn; Ldc; Lum; Lumican; SLRR2D
Gene Symbols: Lum
Molecular weight: 38,265 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene