hnRNP A1 Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May bind to specific miRNA hairpins. (Microbial infection) May play a role in HCV RNA replication. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Nuclear export; RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 15 F3|15 58.58 cM
Cellular Component:  cytoplasm; nucleoplasm; nucleus; ribonucleoprotein complex; spliceosomal complex
Molecular Function:  mRNA binding; nucleic acid binding; RNA binding
Biological Process:  alternative mRNA splicing, via spliceosome; mRNA processing; mRNA transport; RNA splicing
Reference #:  P49312 (UniProtKB)
Alt. Names/Synonyms: D15Ertd119; D15Ertd119e; Fli-2; Hdp; HDP-1; helix destabilizing protein; Helix-destabilizing protein; Heterogeneous nuclear ribonucleoprotein A1; Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; hnRNP A1; hnRNP core protein A1; hnrnp-A1; Hnrnpa1; Hnrpa1; MGC102127; MGC102128; MGC103392; ROA1; Single-strand-binding protein; Tis; Topoisomerase-inhibitor suppressed
Gene Symbols: Hnrnpa1
Molecular weight: 34,196 Da
Basal Isoelectric point: 9.27  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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hnRNP A1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene