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HAO2
Catalyzes the oxidation of L-alpha-hydroxy acids as well as, more slowly, that of L-alpha-amino acids. Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. Liver and kidney. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 1.1.3.15; Oxidoreductase |
| Chromosomal Location of rat Ortholog: 2q34 |
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Cellular Component:
peroxisomal matrix; peroxisome
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Molecular Function:
(S)-2-hydroxy-acid oxidase activity; FMN binding; identical protein binding; oxidoreductase activity
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Biological Process:
fatty acid alpha-oxidation; fatty acid oxidation; mandelate metabolic process
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Reference #:
Q07523
(UniProtKB)
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Alt. Names/Synonyms: (S)-2-hydroxy-acid oxidase, peroxisomal; 2-Hydroxyacid oxidase 2; Hao2; Hao3; HAOX2; Hydroxyacid oxidase 2; hydroxyacid oxidase 2 (long chain); hydroxyacid oxidase 3 (medium-chain); Long chain alpha-hydroxy acid oxidase; Long-chain L-2-hydroxy acid oxidase
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Gene Symbols: Hao2
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Molecular weight:
39,201 Da
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Basal Isoelectric point:
7.55
Predict pI for various phosphorylation states
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