ATG3 an E2-like enzyme essential for Apg8p lipidation. Note: This description may include information from UniProtKB.
Protein type: Autophagy; EC 6.3.2.-; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 16|16 B5
Cellular Component:  cytoplasm; cytoplasmic ubiquitin ligase complex; cytosol
Molecular Function:  Atg12 transferase activity; Atg8 ligase activity; enzyme binding; protein binding; transferase activity; ubiquitin-like protein transferase activity
Biological Process:  autophagosome assembly; autophagy; autophagy of mitochondrion; cellular protein modification process; macroautophagy; mitochondrial fragmentation involved in apoptotic process; negative regulation of phagocytosis; protein transport; protein ubiquitination; regulation of cilium assembly
Reference #:  Q9CPX6 (UniProtKB)
Alt. Names/Synonyms: 2610016C12Rik; APG3; APG3 autophagy 3-like; APG3-like; Apg3l; Atg3; Atg3l; autophagy Apg3p/Aut1p-like; autophagy-related 3 (yeast); autophagy-related 3-like; Autophagy-related protein 3; OTTMUSP00000030762; PC3-96; Ubiquitin-like-conjugating enzyme ATG3
Gene Symbols: Atg3
Molecular weight: 35,796 Da
Basal Isoelectric point: 4.63  Predict pI for various phosphorylation states
CST Pathways:  Autophagy Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein