TUBA1A Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. Expressed at a high level in fetal brain. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 15 F1|15 55.29 cM
Cellular Component:  cytoplasm; cytoplasmic microtubule; cytoplasmic ribonucleoprotein granule; cytoskeleton; membrane raft; microtubule; microtubule cytoskeleton; myelin sheath; neuromuscular junction; recycling endosome
Molecular Function:  GTP binding; GTPase activity; nucleotide binding; protein binding; protein domain specific binding; structural constituent of cytoskeleton
Biological Process:  microtubule cytoskeleton organization; microtubule-based process; mitotic cell cycle; regulation of synapse organization
Reference #:  P68369 (UniProtKB)
Alt. Names/Synonyms: Alpha-tubulin 1; Alpha-tubulin isotype M-alpha-1; Detyrosinated tubulin alpha-1A chain; MGC102097; MGC102098; MGC102099; OTTMUSP00000018539; Talpha1 alpha-tubulin; TBA1A; Tuba; Tuba-; Tuba-1; Tuba1; Tuba1a; Tubulin alpha-1 chain; Tubulin alpha-1A chain; tubulin, alpha 1; tubulin, alpha 1A
Gene Symbols: Tuba1a
Molecular weight: 50,136 Da
Basal Isoelectric point: 4.94  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene