TUBB
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. Ubiquitously expressed with highest levels in spleen, thymus and immature brain. Note: This description may include information from UniProtKB.
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Protein type: Cytoskeletal; Motility/polarity/chemotaxis |
Chromosomal Location of mouse Ortholog: 17|17 B1 |
Cellular Component:
cell body; cytoplasm; cytoplasmic ribonucleoprotein granule; cytoskeleton; cytosol; intercellular bridge; membrane raft; microtubule; microtubule cytoskeleton; mitotic spindle; nuclear envelope lumen; nucleus; protein-containing complex; tubulin complex
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Molecular Function:
GTP binding; GTPase activating protein binding; GTPase activity; metal ion binding; MHC class I protein binding; nucleotide binding; protein domain specific binding; protein-containing complex binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding
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Biological Process:
microtubule cytoskeleton organization; microtubule-based process; mitotic cell cycle; odontoblast differentiation; regulation of synapse organization; spindle assembly
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Reference #:
P99024
(UniProtKB)
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Alt. Names/Synonyms: AA408537; AI596182; B130022C14Rik; M(beta)5; TBB5; TUBB; Tubb5; Tubulin beta-5 chain; tubulin, beta 5; tubulin, beta 5 class I
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Gene Symbols: Tubb5
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Molecular weight:
49,671 Da
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Basal Isoelectric point:
4.78
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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