TAF9B Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription. Belongs to the TAF9 family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: Xq22
Cellular Component:  SAGA complex; transcription factor TFIID complex; transcription factor TFTC complex
Molecular Function:  protein heterodimerization activity; transcription factor binding; transcription regulatory region DNA binding
Biological Process:  DNA-templated transcription, initiation; histone H3 acetylation; negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; positive regulation of cell growth; positive regulation of transcription by RNA polymerase II; programmed cell death; protein stabilization; response to organic cyclic compound; transcription by RNA polymerase II
Reference #:  Q62880 (UniProtKB)
Alt. Names/Synonyms: DN-7; Dn7; Neuronal cell death-related gene in neuron 7; neuronal cell death-related gene in neuron-7; TAF9-like RNA polymerase II TATA box binding protein (TBP)-associated factor 31 kD; TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31 kD; TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; Taf9b; TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor; Taf9l; TAFII31; Transcription initiation factor TFIID subunit 9-like; Transcription initiation factor TFIID subunit 9B; Transcription-associated factor TAFII31L
Gene Symbols: Taf9b
Molecular weight: 28,220 Da
Basal Isoelectric point: 8.45  Predict pI for various phosphorylation states
CST Pathways:  Protein Acetylation
Select Structure to View Below

TAF9B

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene