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TAF9B
Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription. Belongs to the TAF9 family. Note: This description may include information from UniProtKB.
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| Protein type: DNA-binding |
| Chromosomal Location of Human Ortholog: Xq22 |
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Cellular Component:
SAGA complex; transcription factor TFIID complex; transcription factor TFTC complex
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Molecular Function:
protein heterodimerization activity; transcription factor binding; transcription regulatory region DNA binding
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Biological Process:
DNA-templated transcription, initiation; histone H3 acetylation; negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; positive regulation of cell growth; positive regulation of transcription by RNA polymerase II; programmed cell death; protein stabilization; response to organic cyclic compound; transcription by RNA polymerase II
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Reference #:
Q62880
(UniProtKB)
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Alt. Names/Synonyms: DN-7; Dn7; Neuronal cell death-related gene in neuron 7; neuronal cell death-related gene in neuron-7; TAF9-like RNA polymerase II TATA box binding protein (TBP)-associated factor 31 kD; TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31 kD; TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; Taf9b; TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor; Taf9l; TAFII31; Transcription initiation factor TFIID subunit 9-like; Transcription initiation factor TFIID subunit 9B; Transcription-associated factor TAFII31L
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Gene Symbols: Taf9b
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Molecular weight:
28,220 Da
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Basal Isoelectric point:
8.45
Predict pI for various phosphorylation states
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CST Pathways:
Protein Acetylation
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