|
TAF9B
Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription. Belongs to the TAF9 family. Note: This description may include information from UniProtKB.
|
| Protein type: DNA-binding |
| Chromosomal Location of rat Ortholog: Xq22 |
|
Cellular Component:
nucleus; transcription factor TFIID complex; transcription factor TFTC complex
|
|
Molecular Function:
protein heterodimerization activity; RNA polymerase II general transcription initiation factor activity
|
|
Biological Process:
DNA-templated transcription initiation; negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; positive regulation of cell growth; programmed cell death; protein stabilization; response to organic cyclic compound; transcription by RNA polymerase II
|
|
Reference #:
Q62880
(UniProtKB)
|
|
Alt. Names/Synonyms: DN-7; Dn7; Neuronal cell death-related gene in neuron 7; neuronal cell death-related gene in neuron-7; TAF9-like RNA polymerase II TATA box binding protein (TBP)-associated factor 31 kD; TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31 kD; TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; Taf9b; TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor; Taf9l; TAFII31; Transcription initiation factor TFIID subunit 9-like; Transcription initiation factor TFIID subunit 9B; Transcription-associated factor TAFII31L
|
|
Gene Symbols: Taf9b
|
|
Molecular weight:
28,220 Da
|
|
Basal Isoelectric point:
8.45
Predict pI for various phosphorylation states
|
|
CST Pathways:
Protein Acetylation
|
