GIT2 GTPase-activating protein for the ADP ribosylation factor family. 11 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, ARF; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5|5 F
Cellular Component:  calyx of Held; nucleoplasm
Molecular Function:  GTPase activator activity; metal ion binding; protein binding; protein-containing complex binding
Biological Process:  behavioral response to pain; presynaptic modulation of chemical synaptic transmission; regulation of synaptic vesicle exocytosis
Reference #:  Q9JLQ2 (UniProtKB)
Alt. Names/Synonyms: 1500036H07Rik; 5830420E16Rik; 6430510B20Rik; 9630056M03Rik; ARF GAP GIT2; ARF GTPase activating protein 2; ARF GTPase-activating protein GIT2; B230104M05Rik; CAT-2; CAT2; cool associated tyrosine phosphorylated-2; Cool-interacting tyrosine-phosphorylated protein 2; G protein-coupled receptor kinase-interactor 2; Git2; GRK-interacting protein 2; KIAA0148; mKIAA0148; OTTMUSP00000015445; OTTMUSP00000015481
Gene Symbols: Git2
Molecular weight: 78,766 Da
Basal Isoelectric point: 7.64  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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GIT2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene