BASP1 a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2012]
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 2q22
Cellular Component:  cell junction; cytoplasm; growth cone; nuclear speck; nucleus; plasma membrane; signalosome; vesicle
Molecular Function:  calmodulin binding; protein domain specific binding; transcription corepressor activity
Biological Process:  negative regulation of transcription, DNA-dependent; substantia nigra development
Reference #:  Q05175 (UniProtKB)
Alt. Names/Synonyms: 22 kDa neuronal tissue-enriched acidic protein; Basp1; brain abundant, membrane attached signal protein 1; Brain acid soluble protein 1; brain acidic membrane protein; Nap22; Neuronal axonal membrane protein NAP-22
Gene Symbols: Basp1
Molecular weight: 21,790 Da
Basal Isoelectric point: 4.5  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene