RAD52 Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. Belongs to the RAD52 family. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA repair, damage
Chromosomal Location of Human Ortholog: 6 F1|6 56.86 cM
Cellular Component:  nucleus; protein-containing complex; protein-DNA complex
Molecular Function:  DNA binding; identical protein binding; single-stranded DNA binding
Biological Process:  cellular response to DNA damage stimulus; cellular response to oxidative stress; DNA double-strand break processing involved in repair via single-strand annealing; DNA recombinase assembly; DNA recombination; DNA repair; double-strand break repair via homologous recombination; double-strand break repair via single-strand annealing; mitotic recombination; protein homooligomerization; regulation of nucleotide-excision repair
Reference #:  P43352 (UniProtKB)
Alt. Names/Synonyms: DNA repair protein RAD52 homolog; Rad52; RAD52 homolog (S. cerevisiae); RAD52 homolog, DNA repair protein; Rad52yh
Gene Symbols: Rad52
Molecular weight: 46,910 Da
Basal Isoelectric point: 8.24  Predict pI for various phosphorylation states
CST Pathways:  G2/M DNA Damage Checkpoint
Select Structure to View Below

RAD52

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene