DDX41 Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing. Belongs to the DEAD box helicase family. DDX41 subfamily. Note: This description may include information from UniProtKB.
Protein type: EC 3.6.4.13; Helicase; RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of rat Ortholog: 17p14
Cellular Component:  catalytic step 2 spliceosome; endoplasmic reticulum; nucleus; spliceosomal complex
Molecular Function:  ATP binding; DNA binding; hydrolase activity; RNA binding; RNA helicase activity
Biological Process:  cell differentiation; cell population proliferation; cellular response to interferon-beta; defense response to virus; mRNA splicing, via spliceosome; positive regulation of transcription by RNA polymerase II
Reference #:  B2RYL8 (UniProtKB)
Alt. Names/Synonyms: ATP-dependent RNA helicase DDX41; Ddx41; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Gene Symbols: Ddx41
Molecular weight: 69,799 Da
Basal Isoelectric point: 6.37  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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DDX41

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  Reactome  |  BioGPS  |  Pfam  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein