BDP1 Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues. Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily. Expressed in brain, colon and several tumor-derived cell lines. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor)
Chromosomal Location of Human Ortholog: 1 B|1 13.25 cM
Cellular Component:  cytoplasm; nucleus
Molecular Function:  hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity; phosphatase activity; phosphoprotein phosphatase activity; protein binding; protein tyrosine phosphatase activity
Biological Process:  blastocyst formation; dephosphorylation; protein dephosphorylation
Reference #:  Q61152 (UniProtKB)
Alt. Names/Synonyms: Fetal liver phosphatase 1; FLP-1; Flp1; HSCF; protein tyrosine phosphatase, non-receptor type 18; PTN18; PTP-HSCF; PTP-K1; Ptpk1; Ptpn18; Tyrosine-protein phosphatase non-receptor type 18
Gene Symbols: Ptpn18
Molecular weight: 50,202 Da
Basal Isoelectric point: 8.57  Predict pI for various phosphorylation states
CST Pathways:  ErbB/HER Signaling
Select Structure to View Below

BDP1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene