|
CHAT
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. Belongs to the carnitine/choline acetyltransferase family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Acetyltransferase; EC 2.3.1.6; Lipid Metabolism - glycerophospholipid |
| Chromosomal Location of mouse Ortholog: 14 B|14 19.4 cM |
|
Cellular Component:
axon; cytoplasm; neuron projection; neuronal cell body
|
|
Molecular Function:
acyltransferase activity; choline binding; choline O-acetyltransferase activity; transferase activity
|
|
Biological Process:
acetylcholine biosynthetic process; adult walking behavior; chemical synaptic transmission; dendrite development; establishment of synaptic specificity at neuromuscular junction; memory; muscle organ development; neuromuscular synaptic transmission; neuron differentiation; neurotransmitter biosynthetic process; rhythmic behavior; rhythmic excitation
|
|
Reference #:
Q03059
(UniProtKB)
|
|
Alt. Names/Synonyms: B230380D24Rik; ChAT; CHOACTase; Choline acetylase; choline acetyltransferase; Choline O-acetyltransferase; CLAT
|
|
Gene Symbols: Chat
|
|
Molecular weight:
71,853 Da
|
|
Basal Isoelectric point:
7.96
Predict pI for various phosphorylation states
|
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
|
