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PLB
P61016
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| Protein type: Inhibitor; Membrane protein, integral |
| Chromosomal Location of rat Ortholog: 20q11 |
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Cellular Component:
calcium ion-transporting ATPase complex; endoplasmic reticulum membrane; membrane; mitochondrial membrane; protein-containing complex; sarcoplasmic reticulum; sarcoplasmic reticulum membrane; vesicle
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Molecular Function:
ATPase inhibitor activity; identical protein binding; protein binding; protein homodimerization activity
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Biological Process:
acrosome assembly; adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process; calcium ion transport; cardiac muscle tissue development; intracellular calcium ion homeostasis; muscle cell cellular homeostasis; negative regulation of ATP-dependent activity; negative regulation of ATPase-coupled calcium transmembrane transporter activity; negative regulation of calcium ion binding; negative regulation of calcium ion import into sarcoplasmic reticulum; negative regulation of calcium ion transmembrane transporter activity; negative regulation of calcium ion transport; negative regulation of heart contraction; negative regulation of heart rate; Notch signaling pathway; regulation of ATPase-coupled calcium transmembrane transporter activity; regulation of calcium ion import; regulation of calcium ion transport; regulation of cardiac muscle cell contraction; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; regulation of heart contraction; regulation of relaxation of muscle; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; regulation of ryanodine-sensitive calcium-release channel activity; regulation of the force of heart contraction; regulation of the force of heart contraction by cardiac conduction; response to insulin; response to testosterone; response to zinc ion
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Reference #:
P61016
(UniProtKB)
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Alt. Names/Synonyms: Cardiac phospholamban; phospholamban; PLB; Plm; Pln; PPLA
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Gene Symbols: Pln
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Molecular weight:
6,095 Da
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Basal Isoelectric point:
9.15
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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