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SLC5A3
Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family |
| Chromosomal Location of Human Ortholog: 21q22.11 |
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Cellular Component:
integral component of plasma membrane; plasma membrane
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Molecular Function:
myo-inositol:sodium symporter activity
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Biological Process:
glucose transmembrane transport; myo-inositol transport; peripheral nervous system development; regulation of respiratory gaseous exchange; sodium ion transport
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Reference #:
P53794
(UniProtKB)
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Alt. Names/Synonyms: BCW2; human solute carrier family 5, member 3, Sodium/myo-inositol cotransporter; Na(+)/myo-inositol cotransporter; SC5A3; SLC5A3; SMIT; SMIT1; SMIT2; Sodium/myo-inositol cotransporter; sodium/myo-inositol cotransporter 1; Sodium/myo-inositol transporter 1; solute carrier family 5 (inositol transporter), member 3; solute carrier family 5 (inositol transporters), member 3; solute carrier family 5 (sodium/myo-inositol cotransporter), member 3; Solute carrier family 5 member 3
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Gene Symbols: SLC5A3
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Molecular weight:
79,694 Da
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Basal Isoelectric point:
7.01
Predict pI for various phosphorylation states
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