SLC5A3 Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 21q22.11
Cellular Component:  integral component of plasma membrane; plasma membrane
Molecular Function:  myo-inositol:sodium symporter activity
Biological Process:  glucose transmembrane transport; myo-inositol transport; peripheral nervous system development; regulation of respiratory gaseous exchange; sodium ion transport
Reference #:  P53794 (UniProtKB)
Alt. Names/Synonyms: BCW2; human solute carrier family 5, member 3, Sodium/myo-inositol cotransporter; Na(+)/myo-inositol cotransporter; SC5A3; SLC5A3; SMIT; SMIT1; SMIT2; Sodium/myo-inositol cotransporter; sodium/myo-inositol cotransporter 1; Sodium/myo-inositol transporter 1; solute carrier family 5 (inositol transporter), member 3; solute carrier family 5 (inositol transporters), member 3; solute carrier family 5 (sodium/myo-inositol cotransporter), member 3; Solute carrier family 5 member 3
Gene Symbols: SLC5A3
Molecular weight: 79,694 Da
Basal Isoelectric point: 7.01  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB