GIT2
GTPase-activating protein for the ADP ribosylation factor family. 11 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: GAP; GAP, ARF; Motility/polarity/chemotaxis |
Chromosomal Location of human Ortholog: 12q24.11 |
Cellular Component:
nucleoplasm; presynapse; synapse
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Molecular Function:
GTPase activator activity; metal ion binding; protein binding; small GTPase binding
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Biological Process:
brain development; regulation of ARF protein signal transduction; regulation of G protein-coupled receptor signaling pathway; synaptic vesicle recycling
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Reference #:
Q14161
(UniProtKB)
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Alt. Names/Synonyms: ARF GAP GIT2; ARF GTPase-activating protein GIT2; CAT-2; CAT2; cool-associated, tyrosine phosphorylated protein 2; Cool-interacting tyrosine-phosphorylated protein 2; DKFZp686G01261; G protein-coupled receptor kinase interacting ArfGAP 2; G protein-coupled receptor kinase interactor 2; G protein-coupled receptor kinase-interactor 2; GIT ArfGAP 2; GIT2; GRK-interacting protein 2; KIAA0148; MGC760; Paxillin kinase linker; PKL
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Gene Symbols: GIT2
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Molecular weight:
84,543 Da
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Basal Isoelectric point:
6.78
Predict pI for various phosphorylation states
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CST Pathways:
Actin Dynamics
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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