PAG an ubiquitous type III transmembrane adaptor protein that binds to the tyrosine kinase CSK protein. It is thought to be involved in the regulation of T cell activation. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Membrane protein, integral
Chromosomal Location of Human Ortholog: 8q21.13
Cellular Component:  integral component of membrane; membrane raft; plasma membrane
Molecular Function:  protein binding; SH2 domain binding; SH3/SH2 adaptor activity
Biological Process:  adaptive immune response; intracellular signal transduction; positive regulation of signal transduction; regulation of T cell activation; signal transduction; T cell receptor signaling pathway
Reference #:  Q9NWQ8 (UniProtKB)
Alt. Names/Synonyms: CBP; Csk-binding protein; FLJ37858; MGC138364; PAG; PAG1; phosphoprotein associated with glycosphingolipid microdomains 1; Phosphoprotein associated with glycosphingolipid-enriched microdomains 1; Transmembrane adapter protein PAG; Transmembrane phosphoprotein Cbp
Gene Symbols: PAG1
Molecular weight: 46,981 Da
Basal Isoelectric point: 4.57  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene