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PAG
an ubiquitous type III transmembrane adaptor protein that binds to the tyrosine kinase CSK protein. It is thought to be involved in the regulation of T cell activation. Note: This description may include information from UniProtKB.
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| Protein type: Adaptor/scaffold; Membrane protein, integral |
| Chromosomal Location of Human Ortholog: 8q21.13 |
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Cellular Component:
integral component of membrane; membrane raft; plasma membrane
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Molecular Function:
protein binding; SH2 domain binding; SH3/SH2 adaptor activity
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Biological Process:
adaptive immune response; intracellular signal transduction; positive regulation of signal transduction; regulation of T cell activation; signal transduction; T cell receptor signaling pathway
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Reference #:
Q9NWQ8
(UniProtKB)
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Alt. Names/Synonyms: CBP; Csk-binding protein; FLJ37858; MGC138364; PAG; PAG1; phosphoprotein associated with glycosphingolipid microdomains 1; Phosphoprotein associated with glycosphingolipid-enriched microdomains 1; Transmembrane adapter protein PAG; Transmembrane phosphoprotein Cbp
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Gene Symbols: PAG1
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Molecular weight:
46,981 Da
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Basal Isoelectric point:
4.57
Predict pI for various phosphorylation states
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