GOLGA5 a member of the golgin family of proteins, whose members localize to the Golgi. Involved in regulating the architecture of the Golgi apparatus. A coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues. Highly phosphorylated during mitosis. Phosphorylation is barely detectable during interphase. Two splice variant isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Membrane protein, integral
Chromosomal Location of Human Ortholog: 14q32.12
Cellular Component:  cis-Golgi network; Golgi apparatus; Golgi cisterna; Golgi membrane; integral component of membrane; transport vesicle
Molecular Function:  protein homodimerization activity; Rab GTPase binding
Biological Process:  Golgi organization; Golgi vesicle transport
Disease: Thyroid Carcinoma, Papillary
Reference #:  Q8TBA6 (UniProtKB)
Alt. Names/Synonyms: Cell proliferation-inducing gene 31 protein; GOGA5; GOLGA5; golgi autoantigen, golgin subfamily a, 5; golgi integral membrane protein 5; golgin A5; Golgin subfamily A member 5; Golgin-84; GOLIM5; Protein Ret-II; RET-fused gene 5 protein; ret-II; RETII; RFG5
Gene Symbols: GOLGA5
Molecular weight: 83,024 Da
Basal Isoelectric point: 5.6  Predict pI for various phosphorylation states
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GOLGA5

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB