SCGB2A1 May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones. Belongs to the secretoglobin family. Lipophilin subfamily. Expressed in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland. Note: This description may include information from UniProtKB.
Chromosomal Location of human Ortholog: 11q12.3
Cellular Component:  extracellular space
Molecular Function:  protein binding
Biological Process:  androgen receptor signaling pathway
Reference #:  O75556 (UniProtKB)
Alt. Names/Synonyms: Lacryglobin; LIPHC; lipophilin C; Lipophilin-C; LPHC; LPNC; mammaglobin 2; mammaglobin B; Mammaglobin-2; Mammaglobin-B; MGB2; MGC71973; SCGB2A1; Secretoglobin family 2A member 1; secretoglobin, family 2A, member 1; SG2A1; UGB3
Gene Symbols: SCGB2A1
Molecular weight: 10,884 Da
Basal Isoelectric point: 5.48  Predict pI for various phosphorylation states
Select Structure to View Below

SCGB2A1

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein