Lasp-1 a member of the LIM protein subfamily, characterized by a LIM motif and SH3 domain. Functions as an actin-binding protein, possibly in cytoskeletal organization. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q12
Cellular Component:  cortical actin cytoskeleton; cytoplasm
Molecular Function:  actin filament binding; ion transmembrane transporter activity; metal ion binding; protein binding; SH3/SH2 adaptor activity
Biological Process:  ion transmembrane transport; ion transport; positive regulation of signal transduction
Reference #:  Q14847 (UniProtKB)
Alt. Names/Synonyms: LASP-1; LASP1; LIM and SH3 domain protein 1; LIM and SH3 protein 1; Metastatic lymph node gene 50 protein; MLN 50; MLN50
Gene Symbols: LASP1
Molecular weight: 29,717 Da
Basal Isoelectric point: 6.61  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene