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MST4
Mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.7.11.1; Kinase, protein; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; YSK subfamily |
| Chromosomal Location of mouse Ortholog: X|X A5 |
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Cellular Component:
apical plasma membrane; cell periphery; cytoplasm; cytosol; Golgi apparatus; Golgi membrane; Golgi-associated vesicle; membrane; perinuclear region of cytoplasm
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Molecular Function:
ATP binding; identical protein binding; kinase activity; magnesium ion binding; metal ion binding; nucleotide binding; protein homodimerization activity; protein kinase activity; protein serine/threonine kinase activity; transferase activity
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Biological Process:
apoptotic process; cellular response to starvation; microvillus assembly; negative regulation of cell migration; phosphorylation; protein autophosphorylation; protein phosphorylation; regulation of apoptotic process; response to hydrogen peroxide; stress-activated protein kinase signaling cascade
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Reference #:
Q99JT2
(UniProtKB)
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Alt. Names/Synonyms: 2610018G03Rik; Mammalian STE20-like protein kinase 4; Mst; MST-4; Mst3 and SOK1-related kinase; Mst4; OTTMUSP00000019070; RIKEN cDNA 2610018G03 gene; serine/threonine kinase 26; serine/threonine protein kinase MST4; Serine/threonine-protein kinase 26; Serine/threonine-protein kinase MST4; STE20-like kinase MST4; Stk26
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Gene Symbols: Stk26
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Molecular weight:
46,614 Da
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Basal Isoelectric point:
5.12
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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