LIP8 Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 10q24
Cellular Component:  centriole; centrosome; cytosol
Molecular Function:  protein domain specific binding
Biological Process:  centriole replication; centrosome separation; mitotic cytokinetic process; regulation of cilium assembly
Reference #:  XP_220600 (RefSeq)
Alt. Names/Synonyms: centrobin, centriole duplication and spindle assembly protein; centrobin, centrosomal BRCA2 interacting protein; Cntrob; Lip8; LYST-interacting protein 8; RGD1307488
Gene Symbols: Cntrob
Molecular weight: 100,885 Da
Basal Isoelectric point: 5.43  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  BioGPS  |  Entrez-Gene  |  GenPept  |  Ensembl Gene