KIAA1468 Regulates intracellular cholesterol distribution from recycling endosomes to the trans-Golgi network through interactions with RAB11 and OSBP. Functions in membrane tethering and promotes OSBP-mediated cholesterol transfer between RAB11-bound recycling endosomes and OSBP-bound Golgi-like membranes. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 13p11
Cellular Component:  recycling endosome; trans-Golgi network
Biological Process:  intracellular cholesterol transport
Reference #:  D3ZJ01 (UniProtKB)
Alt. Names/Synonyms: hypothetical protein LOC309053; RGD1307235; Similar to RIKEN cDNA 2310035C23
Gene Symbols: RGD1307235
Molecular weight: 134,651 Da
Basal Isoelectric point: 5.16  Predict pI for various phosphorylation states
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KIAA1468

Protein Structure Not Found.

Cross-references to other databases:  BioGPS  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein