IDS Required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Belongs to the sulfatase family. Liver, kidney, lung, and placenta. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.6.13; Glycan Metabolism - glycosaminoglycan degradation; Hydrolase
Chromosomal Location of mouse Ortholog: X A7.2|X 36.01 cM
Cellular Component:  lysosome
Molecular Function:  catalytic activity; hydrolase activity; iduronate-2-sulfatase activity; metal ion binding; protein binding; sulfuric ester hydrolase activity
Reference #:  Q08890 (UniProtKB)
Alt. Names/Synonyms: Alpha-L-iduronate sulfate sulfatase; AW214631; Ids; Iduronate 2-sulfatase; iduronate sulfatase; iduronate-2-sulfatase
Gene Symbols: Ids
Molecular weight: 62,186 Da
Basal Isoelectric point: 5.45  Predict pI for various phosphorylation states
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IDS

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene