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BCAN
May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. Belongs to the aggrecan/versican proteoglycan family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, GPI anchor; Secreted; Secreted, signal peptide |
| Chromosomal Location of human Ortholog: 1q23.1 |
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Cellular Component:
extracellular region; extracellular space; glutamatergic synapse; Golgi lumen; lysosomal lumen; perineuronal net; side of membrane; synapse
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Molecular Function:
carbohydrate binding; hyaluronic acid binding; protein binding
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Biological Process:
cell adhesion; central nervous system development; glial cell differentiation; hippocampus development; positive regulation of neuroblast proliferation; skeletal system development; synapse maturation
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Reference #:
Q96GW7
(UniProtKB)
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Alt. Names/Synonyms: BCAN; BEHAB; Brain-enriched hyaluronan-binding protein; brevican; Brevican core protein; brevican proteoglycan; Chondroitin sulfate proteoglycan 7; chondroitin sulfate proteoglycan BEHAB; chondroitin sulfate proteoglycan BEHAB/brevican; CSPG7; MGC13038; PGCB
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Gene Symbols: BCAN
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Molecular weight:
99,118 Da
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Basal Isoelectric point:
4.57
Predict pI for various phosphorylation states
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